GHK-Cu (Copper Peptide) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine that plays a fundamental role in skin maintenance and systemic tissue repair. It upregulates collagen and elastin synthesis, activates antioxidant enzymes including superoxide dismutase, modulates TGF-β signaling, and promotes wound closure — establishing it as one of the most comprehensively researched actives in cosmetic dermatology. Beyond skin applications, GHK-Cu has demonstrated hair follicle stimulation, anti-inflammatory, and potential neuroprotective properties across a wide body of preclinical and clinical literature.